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Clinical Characteristics of Immunoglobulin M Deposition in Patients with Primary IgA Nephropathy

作者:Feng Shaoqiang

院校:Jinzhou Medical University, China

摘要:IgA nephropathy is a complex renal disease characterized by the deposition of IgA immune complexes within the
glomeruli. This article provides a comprehensive analysis of the pathological classification, clinical features, diagnosis, and
treatment advances in IgA nephropathy. The Oxford classification system offers a standardized approach to the pathological
classification of IgA nephropathy and serves as a reference for prognostic assessment. Additionally, patients with IgA
nephropathy accompanied by IgM deposition exhibit specific clinical manifestations, such as hematuria, proteinuria, and
hypertension. Further research should focus on elucidating the pathogenesis of the disease, identifying biomarkers, developing
individualized treatment strategies, and investigating long-term prognosis and epidemiological characteristics. This review
provides a comprehensive understanding of IgA nephropathy to guide its diagnosis and treatment.

关键词

IgA nephropathy; IgM deposition; pathological classification; Oxford classification; clinical features; diagnosis; treatment; prognosis; biomarkers; individualized treatment; epidemiological characteristics

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参考

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