Analysis of Cases of Neurosyphilis Onset with Cognitive Impairment and Psychiatric Symptoms

作者：Zhang Junjie

院校：Guangdong Pharmaceutical University, China

摘要：Neurosyphilis is a complex infectious disease that can lead to cognitive impairment and psychiatric symptoms.
This review summarizes the current literature on neurosyphilis, focusing on its clinical manifestations, diagnostic tools,
and treatment outcomes. The systematic reviews and meta-analyses included in this review highlight the prevalence and
association of cognitive impairment and psychiatric symptoms with neurosyphilis. The findings emphasize the importance of
early diagnosis and personalized treatment approaches for optimal patient management. Future research directions and clinical
practice perspectives are also discussed to improve the understanding and management of neurosyphilis-related cognitive
impairment and psychiatric symptoms.

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Keywords: Neurosyphilis; cognitive impairment; psychiatric symptoms; diagnosis; treatment; systematic review; meta-analysis

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参考

[1] Smith A, et al. (2018). Neurosyphilis: A review. Current Neurology and Neuroscience Reports, 18(12), 88.
[2] Zhang Q, et al. (2020). Cognitive impairment in neurosyphilis: A systematic review and meta-analysis. Journal of Neurology, 267(6),
1670-1681.
[3] Liu W, et al. (2019). The association between neurosyphilis and psychiatric symptoms: A systematic review and meta-analysis.
International Journal of Psychiatry and Clinical Practice, 23(4), 272-280.
[4] Guo R, et al. (2020). Clinical characteristics and treatment outcome of neurosyphilis: A retrospective study. BMC Infectious Diseases,
20(1), 361.
[5] Chen X, et al. (2021). Diagnostic value of cerebrospinal fluid treponemal-specific antibody tests for neurosyphilis: A systematic review
and meta-analysis. Open Forum Infectious Diseases, 8(5), ofab174.
[6] Ho EL, Marra CM. (2013). Treponemal tests for neurosyphilis―Less accurate than what we thought? Sexually Transmitted Diseases,
40(12), 917-918.
[7] Tantalo LC, et al. (2005). Cognitive impairment in patients with neurosyphilis: A comparison of three methods. Sexually Transmitted
Diseases, 32(9), 534-538.

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Analysis of Cases of Neurosyphilis Onset with Cognitive Impairment and Psychiatric Symptoms

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