Cytogenetic Characteristics and Therapeutic Effects Analysis of Primary Amenorrhea Patients

作者：Wu Jun

院校：Zhejiang Ocean University Donghai Science and Technology College, China

摘要：This paper presents a summary of the research findings discussed in the conversation regarding primary amenorrhea.
The cytogenetic analysis of 214 Chinese women with primary amenorrhea and a retrospective study from a tertiary care
center in South India on chromosomal analysis in amenorrhea were reviewed. Additionally, the role of follicular excess in
polycystic ovaries and its relation to follicular arrest, as well as the treatment of polycystic ovary syndrome in adolescence,
were discussed. The studies highlighted the high prevalence of chromosomal abnormalities in primary amenorrhea patients and
the effectiveness of hormonal therapy, surgical interventions, and lifestyle modifications in improving menstrual regularity and
reproductive health. The future research directions were emphasized, including exploring the molecular mechanisms of specific
chromosomal abnormalities in primary amenorrhea and enhancing genetic counseling and patient communication.

关键词

Primary amenorrhea; cytogenetic analysis; chromosomal abnormalities; follicular excess; follicular arrest; polycystic ovary syndrome; hormonal therapy; surgical intervention; lifestyle modifications; genetic counseling

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[1] Cheng, P. J., Shaw, S. W., Shih, J. C., & Soong, Y. K. (1999). Cytogenetic analysis of 214 Chinese women with primary amenorrhea.
Gynecologic and Obstetric Investigation, 48(2), 134-138.
[2] Babu, K., Ambulkar, P., Kulkarni, R., et al. (2015). Chromosomal analysis in amenorrhea: A retrospective study from a tertiary care center
in South India. Iranian Journal of Reproductive Medicine, 13(4), 203-208.
[3] Jonard, S., & Dewailly, D. (2004). The follicular excess in polycystic ovaries, due to intra-ovarian hyperandrogenism, may be the main
culprit for the follicular arrest. Human Reproduction Update, 10(2), 107-117.
[4] Deligeoroglou, E., Athanasopoulos, N., Tsimaris, P., Dimopoulos, K. D., Economou, E., & Creatsas, G. (2006). Treatment of polycystic
ovary syndrome in adolescence. Hormones, 5(3), 198-212.

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Cytogenetic Characteristics and Therapeutic Effects Analysis of Primary Amenorrhea Patients

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